| ncRNA name | TonEBP siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Mus musculus |
| Tissues/Cell_line | retinas |
| Methods | siRNA injection, immunofluorescence staining, Western blot, sorbitol colorimetric assay |
| Expression pattern | associated |
| Functional description | We performed intravitreal injection of TonEBP siRNA and confirmed the decrease in AR and PKCδ levels. We found that a proapoptotic factor, Bax level was reduced and a survival factor, Bcl2 level was increased after injection of TonEBP siRNA. |
| PubMed ID | 24631337 |
| Year | 2014 |
| Title | Tonicity-responsive enhancer binding protein regulates the expression of aldose reductase and protein kinase C δ in a mouse model of diabetic retinopathy. |
| Drug-related ncRNA | NO |
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